Panama staycation hotels

Central America and Caribbean · Panama

Panama Staycation

The highest-rated hotels across Panama — from boutique city hideaways to landmark luxury resorts. Every stay is hand-picked by Staycation and ranked by real guest scores, with live Agoda rates and one-tap booking.

137
Hotels listed
8.9/ 10
Top picks’ avg score
22
5-star properties
Browse all Panama hotels →

Where to Stay

Top Cities in Panama

Panama City staycation hotels
Panama City
Panama · 78 hotels
Bocas del Toro staycation hotels
Bocas del Toro
Panama · 13 hotels
Boquete staycation hotels
Boquete
Panama · 9 hotels
David staycation hotels
David
Panama · 8 hotels
Tocumen staycation hotels
Tocumen
Panama · 4 hotels
Las Escobas del Venado staycation hotels
Las Escobas del Venado
Panama · 3 hotels
Los Naranjos staycation hotels
Los Naranjos
Panama · 2 hotels
Gamboa staycation hotels
Gamboa
Panama · 2 hotels
Bastimentos staycation hotels
Bastimentos
Panama · 2 hotels
El Chirú staycation hotels
El Chirú
Panama · 1 hotel
Isla Cristobal staycation hotels
Isla Cristobal
Panama · 1 hotel
El Pajonal staycation hotels
El Pajonal
Panama · 1 hotel

Curated by Staycation

Top Panama Staycation Hotels

Sofitel Legend Casco ViejoHotel
Panama City, Panama
Sofitel Legend Casco Viejo
★★★★★
📶 Free WiFi
9.5Exceptional
Per night
$536 USD/night
+ taxes & fees
Intercontinental Miramar Panama By IHGHotel
Panama City, Panama
Intercontinental Miramar Panama By IHG
★★★★
📶 Free WiFi
8.9Excellent
Per night
$352 USD/night
+ taxes & fees
La Concordia Boutique HotelHotel
Panama City, Panama
La Concordia Boutique Hotel
★★★★
📶 Free WiFi
9.7Exceptional
Per night
$320 USD/night
+ taxes & fees
JW Marriott PanamaHotel
Panama City, Panama
JW Marriott Panama
★★★★★
8.3Excellent
Per night
$303 USD/night
+ taxes & fees
The Santa Maria, a Luxury Collection Hotel & Golf Resort, Panama CityHotel
Panama City, Panama
The Santa Maria, a Luxury Collection Hotel & Golf Resort, Panama City
★★★★★
🍳 Free breakfast
8.7Excellent
Per night
$299 USD/night
+ taxes & fees
W PanamaHotel
Panama City, Panama
W Panama
★★★★★
8.3Excellent
Per night
$289 USD/night
+ taxes & fees
Waldorf Astoria PanamaHotel
Panama City, Panama
Waldorf Astoria Panama
★★★★★
📶 Free WiFi
9.1Exceptional
Per night
$284 USD/night
+ taxes & fees
Hilton PanamaHotel
Panama City, Panama
Hilton Panama
★★★★
📶 Free WiFi
9.1Exceptional
Per night
$284 USD/night
+ taxes & fees
The Buenaventura Golf & Beach Resort Panama, Autograph CollectionHotel
El Chirú, Panama
The Buenaventura Golf & Beach Resort Panama, Autograph Collection
★★★★★
🍳 Free breakfast
9.0Exceptional
Per night
$263 USD/night
+ taxes & fees
The Westin PanamaHotel
Panama City, Panama
The Westin Panama
★★★★
9.5Exceptional
Per night
$240 USD/night
+ taxes & fees
The Westin Playa Bonita PanamaHotel
Panama City, Panama
The Westin Playa Bonita Panama
★★★★★
8.8Excellent
Per night
$224 USD/night
+ taxes & fees
Hyatt Regency Panama CityHotel
Panama City, Panama
Hyatt Regency Panama City
★★★★★
8.4Excellent
Per night
$188 USD/night
+ taxes & fees
View all Panama hotels →

The Best Panama Staycation Hotels

Whether you’re planning a weekend staycation or a longer escape across Panama, Staycation curates the finest places to stay — from boutique hideaways and heritage hotels to iconic luxury properties. Every hotel is ranked by real guest scores, so you can book with confidence.

Rates are powered by Agoda, with live availability and competitive pricing. Start in Panama City, Bocas del Toro or Boquete, or explore every Panama destination.