Panama City staycation hotels

Central America and Caribbean · Panama

Your Panama City Staycation

Hand-picked hotels in Panama City — ranked by real guest scores, with live Agoda rates and one-tap booking. From boutique hideaways to luxury icons, every stay is curated by Staycation.

20
Curated stays
8.7/ 10
Average guest score
12
5-star properties

20 properties · curated by Staycation

Riu Plaza PanamaHotel
Panama City, Panama
Riu Plaza Panama
★★★★★
🍳 Free breakfast📶 Free WiFi
8.9Excellent
Per night
HK$1,230 HKD/night
HK$4,921 HKD
+ taxes & fees
Bristol Panama, a Registry Collection HotelHotel
Panama City, Panama
Bristol Panama, a Registry Collection Hotel
★★★★★
📶 Free WiFi
9.2Exceptional
Per night
HK$1,657 HKD/night
+ taxes & fees
Waldorf Astoria PanamaHotel
Panama City, Panama
Waldorf Astoria Panama
★★★★★
📶 Free WiFi
9.1Exceptional
Per night
HK$2,368 HKD/night
+ taxes & fees
Sofitel Legend Casco ViejoHotel
Panama City, Panama
Sofitel Legend Casco Viejo
★★★★★
📶 Free WiFi
9.5Exceptional
Per night
HK$4,132 HKD/night
+ taxes & fees
The Westin Playa Bonita PanamaHotel
Panama City, Panama
The Westin Playa Bonita Panama
★★★★★
8.8Excellent
Per night
HK$1,759 HKD/night
+ taxes & fees
The Santa Maria, a Luxury Collection Hotel & Golf Resort, Panama CityHotel
Panama City, Panama
The Santa Maria, a Luxury Collection Hotel & Golf Resort, Panama City
★★★★★
🍳 Free breakfast
8.7Excellent
Per night
HK$2,761 HKD/night
+ taxes & fees
JW Marriott PanamaHotel
Panama City, Panama
JW Marriott Panama
★★★★★
8.3Excellent
Per night
HK$3,070 HKD/night
+ taxes & fees
W PanamaHotel
Panama City, Panama
W Panama
★★★★★
8.3Excellent
Per night
HK$2,568 HKD/night
+ taxes & fees
Renaissance Panama City HotelHotel
Panama City, Panama
Renaissance Panama City Hotel
★★★★★
8.8Excellent
Per night
HK$1,059 HKD/night
+ taxes & fees
La Résidence PanamáHotel
Panama City, Panama
La Résidence Panamá
★★★★★
0.0Good
Continental Hotel & CasinoHotel
Panama City, Panama
Continental Hotel & Casino
★★★★★
7.6Very Good
Veneto Hotel & CasinoHotel
Panama City, Panama
Veneto Hotel & Casino
★★★★★
7.4Very Good
Sortis Hotel, Spa & Casino, Autograph CollectionHotel
Panama City, Panama
Sortis Hotel, Spa & Casino, Autograph Collection
★★★★★
8.5Excellent
Per night
HK$2,354 HKD/night
+ taxes & fees
Hyatt Regency Panama CityHotel
Panama City, Panama
Hyatt Regency Panama City
★★★★★
8.4Excellent
Per night
HK$1,468 HKD/night
+ taxes & fees
Hotel La Compañía Casco AntiguoHotel
Panama City, Panama
Hotel La Compañía Casco Antiguo
★★★★★
0.0Good
Ramada Plaza by Wyndham Panama Punta PacificaHotel
Panama City, Panama
Ramada Plaza by Wyndham Panama Punta Pacifica
★★★★
9.3Exceptional
Plaza Paitilla InnHotel
Panama City, Panama
Plaza Paitilla Inn
★★★★
📶 Free WiFi
9.1Exceptional
Per night
HK$809 HKD/night
+ taxes & fees
The Executive HotelHotel
Panama City, Panama
The Executive Hotel
★★★★
9.2Exceptional
Waymore Hotel Spa & CasinoHotel
Panama City, Panama
Waymore Hotel Spa & Casino
★★★★
🍳 Free breakfast📶 Free WiFi
9.1Exceptional
Per night
HK$807 HKD/night
+ taxes & fees
Central Hotel PanamaHotel
Panama City, Panama
Central Hotel Panama
★★★★
9.0Exceptional
Per night
HK$1,458 HKD/night
+ taxes & fees

The Best Panama City Staycation Hotels

Whether you’re planning a weekend staycation in Panama City or a longer escape acrossPanama, Staycation curates the finest places to stay — from boutique hideaways and heritage hotels to iconic luxury properties. Every Panama City staycation hotel is ranked by real guest scores, so you can book with confidence.

Rates are powered by Agoda, with live availability and competitive pricing. Pick your dates above to see tonight’s best Panama City staycation deals, or explore other destinations in Central America and Caribbean.