Durham (NC) staycation hotels

North America · United States

Your Durham (NC) Staycation

Hand-picked hotels in Durham (NC) — ranked by real guest scores, with live Agoda rates and one-tap booking. From boutique hideaways to luxury icons, every stay is curated by Staycation.

54
Curated stays
8.4/ 10
Average guest score

54 properties · curated by Staycation

JB Duke HotelHotel
Durham (NC), United States
JB Duke Hotel
★★★★
📶 Free WiFi
8.4Excellent
For your dates
$535 USD
Washington Duke Inn & Golf ClubHotel
Durham (NC), United States
Washington Duke Inn & Golf Club
★★★★
📶 Free WiFi
9.5Exceptional
For your dates
$400 USD
Aloft by Marriott Durham DowntownHotel
Durham (NC), United States
Aloft by Marriott Durham Downtown
★★★
9.7Exceptional
For your dates
$370 USD
21c Museum Hotel DurhamHotel
Durham (NC), United States
21c Museum Hotel Durham
★★★★
📶 Free WiFi
8.7Excellent
For your dates
$269 USD
Residence Inn by Marriott Durham McPherson/Duke University Medical Center AreaHotel
Durham (NC), United States
Residence Inn by Marriott Durham McPherson/Duke University Medical Center Area
★★★
🍳 Free breakfast
5.6Good
For your dates
$263 USD
Durham Marriott City CenterHotel
Durham (NC), United States
Durham Marriott City Center
★★★★
8.8Excellent
For your dates
$246 USD
AC Hotel DurhamHotel
Durham (NC), United States
AC Hotel Durham
★★★
9.2Exceptional
For your dates
$228 USD
SpringHill Suites by Marriott Durham City ViewHotel
Durham (NC), United States
SpringHill Suites by Marriott Durham City View
★★★★
🍳 Free breakfast📶 Free WiFi
8.4Excellent
For your dates
$210 USD
Home2 Suites by Hilton Durham Chapel HillHotel
Durham (NC), United States
Home2 Suites by Hilton Durham Chapel Hill
★★★
🍳 Free breakfast📶 Free WiFi
9.0Exceptional
For your dates
$209 USD
Holiday Inn Express Chapel Hill By IHGHotel
Durham (NC), United States
Holiday Inn Express Chapel Hill By IHG
★★★
🍳 Free breakfast📶 Free WiFi
8.6Excellent
For your dates
$169 USD
SpringHill Suites by Marriott Durham Chapel HillHotel
Durham (NC), United States
SpringHill Suites by Marriott Durham Chapel Hill
★★★
🍳 Free breakfast
9.4Exceptional
For your dates
$169 USD
Staybridge Suites Of Durham - Chapel Hill - RTP By IHGHotel
Durham (NC), United States
Staybridge Suites Of Durham - Chapel Hill - RTP By IHG
★★★
🍳 Free breakfast📶 Free WiFi
9.2Exceptional
For your dates
$166 USD
Unscripted DurhamHotel
Durham (NC), United States
Unscripted Durham
★★★★
8.2Excellent
For your dates
$162 USD
Delta Hotels by Marriott Raleigh-Durham at Research Triangle ParkHotel
Durham (NC), United States
Delta Hotels by Marriott Raleigh-Durham at Research Triangle Park
★★★★
9.2Exceptional
For your dates
$161 USD
Homewood Suites by Hilton Durham - Chapel Hill I-40 & Hwy. 15-501Hotel
Durham (NC), United States
Homewood Suites by Hilton Durham - Chapel Hill I-40 & Hwy. 15-501
★★★
🍳 Free breakfast📶 Free WiFi
9.3Exceptional
For your dates
$161 USD
Fairfield by Marriott Inn & Suites DurhamHotel
Durham (NC), United States
Fairfield by Marriott Inn & Suites Durham
★★★
🍳 Free breakfast
7.9Very Good
For your dates
$152 USD
Hampton Inn & Suites Durham/North I-85Hotel
Durham (NC), United States
Hampton Inn & Suites Durham/North I-85
★★★
🍳 Free breakfast📶 Free WiFi
9.2Exceptional
For your dates
$149 USD
Hampton Inn & Suites Durham University Medical CenterHotel
Durham (NC), United States
Hampton Inn & Suites Durham University Medical Center
★★★
🍳 Free breakfast📶 Free WiFi
9.8Exceptional
For your dates
$147 USD
Fairfield by Marriott Inn & Suites Durham SouthpointHotel
Durham (NC), United States
Fairfield by Marriott Inn & Suites Durham Southpoint
★★★
🍳 Free breakfast
8.4Excellent
For your dates
$144 USD
Sheraton Imperial Hotel Raleigh-Durham Airport at Research Triangle ParkHotel
Durham (NC), United States
Sheraton Imperial Hotel Raleigh-Durham Airport at Research Triangle Park
★★★★
9.7Exceptional
For your dates
$142 USD
Holiday Inn Express Durham By IHGHotel
Durham (NC), United States
Holiday Inn Express Durham By IHG
★★★
🍳 Free breakfast📶 Free WiFi
9.4Exceptional
For your dates
$140 USD
Millennium Hotel DurhamHotel
Durham (NC), United States
Millennium Hotel Durham
★★★
🍳 Free breakfast📶 Free WiFi
7.8Very Good
For your dates
$140 USD
Hampton Inn & Suites Chapel Hill/DurhamHotel
Durham (NC), United States
Hampton Inn & Suites Chapel Hill/Durham
★★★
🍳 Free breakfast📶 Free WiFi
8.6Excellent
For your dates
$138 USD
Holiday Inn Express Hotel & Suites Research Triangle Park By IHGHotel
Durham (NC), United States
Holiday Inn Express Hotel & Suites Research Triangle Park By IHG
★★★
🍳 Free breakfast📶 Free WiFi
8.7Excellent
For your dates
$136 USD
Homewood Suites by Hilton Raleigh - Durham AP/Research TriangleHotel
Durham (NC), United States
Homewood Suites by Hilton Raleigh - Durham AP/Research Triangle
★★★
🍳 Free breakfast📶 Free WiFi
8.6Excellent
For your dates
$131 USD
La Quinta Inn & Suites by Wyndham Univ Area Chapel HillHotel
Durham (NC), United States
La Quinta Inn & Suites by Wyndham Univ Area Chapel Hill
★★★
📶 Free WiFi
8.4Excellent
For your dates
$129 USD
Marriott Raleigh Durham Research Triangle ParkHotel
Durham (NC), United States
Marriott Raleigh Durham Research Triangle Park
★★★★
7.7Very Good
For your dates
$127 USD
Hilton Durham Near Duke UniversityHotel
Durham (NC), United States
Hilton Durham Near Duke University
★★★
📶 Free WiFi
8.4Excellent
For your dates
$126 USD
DoubleTree by Hilton Raleigh - Durham Airport at Research Triangle ParkHotel
Durham (NC), United States
DoubleTree by Hilton Raleigh - Durham Airport at Research Triangle Park
★★★★
📶 Free WiFi
9.0Exceptional
For your dates
$122 USD
DoubleTree Suites by Hilton Raleigh - DurhamHotel
Durham (NC), United States
DoubleTree Suites by Hilton Raleigh - Durham
★★★
📶 Free WiFi
8.9Excellent
For your dates
$119 USD
SpringHill Suites by Marriott Raleigh-Durham Airport/Research Triangle ParkHotel
Durham (NC), United States
SpringHill Suites by Marriott Raleigh-Durham Airport/Research Triangle Park
★★★
🍳 Free breakfast
8.0Excellent
For your dates
$118 USD
Comfort Inn & Suites Durham near Duke UniversityHotel
Durham (NC), United States
Comfort Inn & Suites Durham near Duke University
★★★
🍳 Free breakfast📶 Free WiFi
8.9Excellent
For your dates
$117 USD
Wingate by Wyndham Raleigh Durham / AirportHotel
Durham (NC), United States
Wingate by Wyndham Raleigh Durham / Airport
★★★
🍳 Free breakfast📶 Free WiFi
8.1Excellent
For your dates
$116 USD
Sonesta Select Durham Research Triangle ParkHotel
Durham (NC), United States
Sonesta Select Durham Research Triangle Park
★★★
📶 Free WiFi
8.2Excellent
For your dates
$114 USD
Courtyard by Marriott Durham Near Duke University/DowntownHotel
Durham (NC), United States
Courtyard by Marriott Durham Near Duke University/Downtown
★★★
8.6Excellent
For your dates
$114 USD
Clarion Pointe Durham Research Triangle ParkHotel
Durham (NC), United States
Clarion Pointe Durham Research Triangle Park
★★★
🍳 Free breakfast📶 Free WiFi
8.3Excellent
For your dates
$113 USD
Comfort Inn University Durham - Chapel HillHotel
Durham (NC), United States
Comfort Inn University Durham - Chapel Hill
★★★
🍳 Free breakfast📶 Free WiFi
8.2Excellent
For your dates
$113 USD
Hilton Garden Inn Durham SouthpointHotel
Durham (NC), United States
Hilton Garden Inn Durham Southpoint
★★★
📶 Free WiFi
8.4Excellent
For your dates
$108 USD
Hilton Garden Inn Raleigh-Durham/Research Triangle ParkHotel
Durham (NC), United States
Hilton Garden Inn Raleigh-Durham/Research Triangle Park
★★★
📶 Free WiFi
9.5Exceptional
For your dates
$101 USD
Extended Stay America Suites - Raleigh - RTP - 4919 Miami Blvd.Hotel
Durham (NC), United States
Extended Stay America Suites - Raleigh - RTP - 4919 Miami Blvd.
★★★
🍳 Free breakfast📶 Free WiFi
7.3Very Good
For your dates
$98 USD
La Quinta Inn & Suites by Wyndham Raleigh/Durham SouthpointHotel
Durham (NC), United States
La Quinta Inn & Suites by Wyndham Raleigh/Durham Southpoint
★★★
📶 Free WiFi
6.9Good
For your dates
$97 USD
Extended Stay America Select Suites - Durham - UniversityHotel
Durham (NC), United States
Extended Stay America Select Suites - Durham - University
★★
📶 Free WiFi
8.5Excellent
For your dates
$95 USD
Candlewood Suites Durham By IHGHotel
Durham (NC), United States
Candlewood Suites Durham By IHG
★★★
📶 Free WiFi
8.0Excellent
For your dates
$89 USD
Sleep Inn Raleigh Durham AirportHotel
Durham (NC), United States
Sleep Inn Raleigh Durham Airport
★★★
🍳 Free breakfast📶 Free WiFi
7.3Very Good
For your dates
$86 USD
Extended Stay America Select Suites - Raleigh - RTP - 4610 Miami Blvd.Hotel
Durham (NC), United States
Extended Stay America Select Suites - Raleigh - RTP - 4610 Miami Blvd.
★★★
📶 Free WiFi
8.5Excellent
For your dates
$85 USD
Red Roof Inn Durham - Duke Univ Medical CenterHotel
Durham (NC), United States
Red Roof Inn Durham - Duke Univ Medical Center
★★
📶 Free WiFi
7.4Very Good
For your dates
$78 USD
SureStay Plus by Best Western Durham Medical CenterHotel
Durham (NC), United States
SureStay Plus by Best Western Durham Medical Center
📶 Free WiFi
7.1Very Good
For your dates
$76 USD
Red Roof Inn Durham - Triangle ParkHotel
Durham (NC), United States
Red Roof Inn Durham - Triangle Park
★★
📶 Free WiFi
7.2Very Good
For your dates
$74 USD
Suburban Studios Durham-RaleighHotel
Durham (NC), United States
Suburban Studios Durham-Raleigh
★★
📶 Free WiFi
4.8Good
For your dates
$63 USD
Econo Lodge Research Triangle ParkHotel
Durham (NC), United States
Econo Lodge Research Triangle Park
★★
🍳 Free breakfast📶 Free WiFi
7.9Very Good
For your dates
$61 USD
OYO Hotel Durham West HillsHotel
Durham (NC), United States
OYO Hotel Durham West Hills
★★★
📶 Free WiFi
7.7Very Good
For your dates
$58 USD
Home2 Suites by Hilton Durham University Medical CenterHotel
Durham (NC), United States
Home2 Suites by Hilton Durham University Medical Center
★★★
10.0Exceptional
Hilton Garden Inn Durham/University Medical CenterHotel
Durham (NC), United States
Hilton Garden Inn Durham/University Medical Center
★★★
8.8Excellent
Super 8 By Wyndham Durham/University Area NcHotel
Durham (NC), United States
Super 8 By Wyndham Durham/University Area Nc
★★
6.8Good

The Best Durham (NC) Staycation Hotels

Whether you’re planning a weekend staycation in Durham (NC) or a longer escape acrossUnited States, Staycation curates the finest places to stay — from boutique hideaways and heritage hotels to iconic luxury properties. Every Durham (NC) staycation hotel is ranked by real guest scores, so you can book with confidence.

Rates are powered by Agoda, with live availability and competitive pricing. Pick your dates above to see tonight’s best Durham (NC) staycation deals, or explore other destinations in North America.